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Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis
The ability to extinguish a viral population of fixed reproductive capacity by causing small changes in the mutation rate is referred to as lethal mutagenesis and is a corollary of population genetics theory. Here we show that coxsackievirus B3 (CVB3) exhibits reduced mutational robustness relative...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302263/ https://ncbi.nlm.nih.gov/pubmed/22190724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05712-11 |
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