Φορτώνει......
Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues
RNA viruses exhibit extraordinarily high mutation rates during genome replication. Nonnatural ribonucleosides that can increase the mutation rate of RNA viruses by acting as ambiguous substrates during replication have been explored as antiviral agents acting through lethal mutagenesis. We have synt...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258490/ https://ncbi.nlm.nih.gov/pubmed/18180344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01056-07 |
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