Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue

Lethal mutagenesis is the mechanism of action of ribavirin against poliovirus (PV) and numerous other RNA viruses. However, there is still considerable debate regarding the mechanism of action of ribavirin against a variety of RNA viruses. Here we show by using T7 RNA polymerase-mediated production...

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Detaylı Bibliyografya
Asıl Yazarlar: Graci, Jason D., Harki, Daniel A., Korneeva, Victoria S., Edathil, Jocelyn P., Too, Kathleen, Franco, David, Smidansky, Eric D., Paul, Aniko V., Peterson, Blake R., Brown, Daniel M., Loakes, David, Cameron, Craig E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045539/
https://ncbi.nlm.nih.gov/pubmed/17686844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01028-07
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