Separation of presenilin function in amyloid β-peptide generation and endoproteolysis of Notch

類似資料

• Presenilin-dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
  著者:: Sastre, Magdalena, 等
  出版事項: (2001)
• Three-Amino Acid Spacing of Presenilin Endoproteolysis Suggests a General Stepwise Cleavage of γ-Secretase-Mediated Intramembrane Proteolysis
  著者:: Fukumori, Akio, 等
  出版事項: (2010)
• Presenilin and nicastrin regulate each other and determine amyloid β-peptide production via complex formation
  著者:: Edbauer, Dieter, 等
  出版事項: (2002)
• The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity
  著者:: Kaether, Christoph, 等
  出版事項: (2004)
• Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Aβ(42) production
  著者:: Moehlmann, Tobias, 等
  出版事項: (2002)