Presenilin and nicastrin regulate each other and determine amyloid β-peptide production via complex formation

Những quyển sách tương tự

• The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity
  Bằng: Kaether, Christoph, et al.
  Được phát hành: (2004)
• Presenilin-1 affects trafficking and processing of βAPP and is targeted in a complex with nicastrin to the plasma membrane
  Bằng: Kaether, Christoph, et al.
  Được phát hành: (2002)
• Separation of presenilin function in amyloid β-peptide generation and endoproteolysis of Notch
  Bằng: Kulic, Luka, et al.
  Được phát hành: (2000)
• Generation of Amyloid-β Is Reduced by the Interaction of Calreticulin with Amyloid Precursor Protein, Presenilin and Nicastrin
  Bằng: Stemmer, Nina, et al.
  Được phát hành: (2013)
• Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Aβ(42) production
  Bằng: Moehlmann, Tobias, et al.
  Được phát hành: (2002)