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Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

The conformational change in amyloid β (Aβ) peptide from its monomeric form to aggregates is crucial in the pathogenesis of Alzheimer's disease (AD). In the healthy brain, some unidentified chaperones appear to prevent the aggregation of Aβ. Here we reported that lipocalin-type prostaglandin D...

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מידע ביבליוגרפי
Main Authors: Kanekiyo, Takahisa, Ban, Tadato, Aritake, Kosuke, Huang, Zhi-Li, Qu, Wei-Min, Okazaki, Issay, Mohri, Ikuko, Murayama, Shigeo, Ozono, Keiichi, Taniike, Masako, Goto, Yuji, Urade, Yoshihiro
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851035/
https://ncbi.nlm.nih.gov/pubmed/17404210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701585104
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