Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

The conformational change in amyloid β (Aβ) peptide from its monomeric form to aggregates is crucial in the pathogenesis of Alzheimer's disease (AD). In the healthy brain, some unidentified chaperones appear to prevent the aggregation of Aβ. Here we reported that lipocalin-type prostaglandin D...

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Dades bibliogràfiques
Autors principals: Kanekiyo, Takahisa, Ban, Tadato, Aritake, Kosuke, Huang, Zhi-Li, Qu, Wei-Min, Okazaki, Issay, Mohri, Ikuko, Murayama, Shigeo, Ozono, Keiichi, Taniike, Masako, Goto, Yuji, Urade, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851035/
https://ncbi.nlm.nih.gov/pubmed/17404210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701585104
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