Perineuronal Oligodendrocytes Protect against Neuronal Apoptosis through the Production of Lipocalin-Type Prostaglandin D Synthase in a Genetic Demyelinating Model

The genetic demyelinating mouse “twitcher” is a model of the human globoid cell leukodystrophy, caused by galactosylceramidase (GALC) deficiency. Demyelination in the twitcher brain is secondary to apoptotic death of oligodendrocytes (OLs). Lipocalin-type prostaglandin (PG) D synthase (L-PGDS), a pr...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Taniike, Masako, Mohri, Ikuko, Eguchi, Naomi, Beuckmann, Carsten T., Suzuki, Kinuko, Urade, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757748/
https://ncbi.nlm.nih.gov/pubmed/12077186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-12-04885.2002
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