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Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

The conformational change in amyloid β (Aβ) peptide from its monomeric form to aggregates is crucial in the pathogenesis of Alzheimer's disease (AD). In the healthy brain, some unidentified chaperones appear to prevent the aggregation of Aβ. Here we reported that lipocalin-type prostaglandin D...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kanekiyo, Takahisa, Ban, Tadato, Aritake, Kosuke, Huang, Zhi-Li, Qu, Wei-Min, Okazaki, Issay, Mohri, Ikuko, Murayama, Shigeo, Ozono, Keiichi, Taniike, Masako, Goto, Yuji, Urade, Yoshihiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851035/
https://ncbi.nlm.nih.gov/pubmed/17404210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701585104
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