PHOSPHORYLATION OF β-CATENIN BY AKT PROMOTES β -CATENIN TRANSCRIPTIONAL ACTIVITY

Increased transcriptional activity of β -catenin resulting from Wnt/Wingless dependent or independent signaling has been detected in many types of human cancer, but the underlying mechanism of Wnt-independent regulation is poorly understood. We have demonstrated that AKT, which is activated downstre...

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Main Authors: Fang, Dexing, Hawke, David, Zheng, Yanhua, Xia, Yan, Meisenhelder, Jill, Nika, Heinz, Mills, Gordon B., Kobayashi, Ryuji, Hunter, Tony, Lu, Zhimin
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850976/
https://ncbi.nlm.nih.gov/pubmed/17287208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611871200
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