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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

Although genetic analysis has demonstrated that members of the winged helix, or forkhead, family of transcription factors play pivotal roles in the regulation of cellular differentiation and proliferation, both during development and in the adult, little is known of the mechanisms underlying their r...

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Bibliographische Detailangaben
Hauptverfasser: Biggs, William H., Meisenhelder, Jill, Hunter, Tony, Cavenee, Webster K., Arden, Karen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22101/
https://ncbi.nlm.nih.gov/pubmed/10377430
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