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PHOSPHORYLATION OF β-CATENIN BY AKT PROMOTES β -CATENIN TRANSCRIPTIONAL ACTIVITY
Increased transcriptional activity of β -catenin resulting from Wnt/Wingless dependent or independent signaling has been detected in many types of human cancer, but the underlying mechanism of Wnt-independent regulation is poorly understood. We have demonstrated that AKT, which is activated downstre...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850976/ https://ncbi.nlm.nih.gov/pubmed/17287208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611871200 |
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