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The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin ()
Interferon-β (IFN-β) is a critical antiviral cytokine that is capable of modulating the systemic immune response. The transcriptional induction of IFN-β is a highly regulated process, involving the activation of pattern recognition receptors and their downstream signaling pathways. The Akt family of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658160/ https://ncbi.nlm.nih.gov/pubmed/22904301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201669 |
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