Functional interaction between the Werner Syndrome protein and DNA polymerase δ
Werner Syndrome (WS) is an inherited disease characterized by premature onset of aging, increased cancer incidence, and genomic instability. The WS gene encodes a 1,432-amino acid polypeptide (WRN) with a central domain homologous to the RecQ family of DNA helicases. Purified WRN unwinds DNA with 3′...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18279/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10781066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.9.4603 |
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