Загрузка...

The Werner Syndrome Exonuclease Facilitates DNA Degradation and High Fidelity DNA Polymerization by Human DNA Polymerase δ

DNA Polymerase δ (Pol δ) and the Werner syndrome protein, WRN, are involved in maintaining cellular genomic stability. Pol δ synthesizes the lagging strand during replication of genomic DNA and also functions in the synthesis steps of DNA repair and recombination. WRN is a member of the RecQ helicas...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Kamath-Loeb, Ashwini S., Shen, Jiang-Cheng, Schmitt, Michael W., Loeb, Lawrence A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320997/
https://ncbi.nlm.nih.gov/pubmed/22351772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332577
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!