טוען...
High Fidelity and Lesion Bypass Capability of Human DNA Polymerase δ
DNA polymerase δ (Pol δ) is one of the main replicative DNA polymerases in human cells and therefore is a critical determinant of the overall accuracy of DNA synthesis. Here we document the fidelity of a human Pol δ holoenzyme and systematically score the types of mutations that the enzyme generates...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774493/ https://ncbi.nlm.nih.gov/pubmed/19540301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2009.06.007 |
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