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Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
When a high-fidelity DNA polymerase encounters certain DNA-damage sites, its progress can be stalled and one or more lesion-bypass polymerases are recruited to transit the lesion. Here, we consider two representative types of lesions: (i) 7,8-dihydro-8-oxogua-nine (8-oxoG), a small, highly prevalent...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717799/ https://ncbi.nlm.nih.gov/pubmed/18407502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2008.02.004 |
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