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Lesion processing: high-fidelity versus lesion-bypass DNA polymerases

When a high-fidelity DNA polymerase encounters certain DNA-damage sites, its progress can be stalled and one or more lesion-bypass polymerases are recruited to transit the lesion. Here, we consider two representative types of lesions: (i) 7,8-dihydro-8-oxogua-nine (8-oxoG), a small, highly prevalent...

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Bibliografski detalji
Glavni autori: Broyde, Suse, Wang, Lihua, Rechkoblit, Olga, Geacintov, Nicholas E., Patel, Dinshaw J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717799/
https://ncbi.nlm.nih.gov/pubmed/18407502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2008.02.004
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