Caricamento...

Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion

7,8-dihydro-8-oxoguanine (oxoG), the predominant lesion formed following oxidative damage of DNA by reactive oxygen species, is processed differently by replicative and bypass polymerases. Our kinetic primer extension studies demonstrate that the bypass polymerase Dpo4 preferentially inserts C oppos...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Rechkoblit, Olga, Malinina, Lucy, Cheng, Yuan, Kuryavyi, Vitaly, Broyde, Suse, Geacintov, Nicholas E, Patel, Dinshaw J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325099/
https://ncbi.nlm.nih.gov/pubmed/16379496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040011
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !