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Glycoprotein Ibα forms disulfide bonds with 2 glycoprotein Ibβ subunits in the resting platelet

It is widely accepted that glycoprotein (GP) Ib contains one Ibα and one Ibβ subunit that are connected by a disulfide bond. It is unclear which Cys residue in Ibα, C484 or C485, forms the disulfide bond with Ibβ. Using mutagenesis studies in transfected Chinese hamster ovary (CHO) cells, we found t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Luo, Shi-Zhong, Mo, Xi, Afshar-Kharghan, Vahid, Srinivasan, Sankaranarayanan, López, José A., Li, Renhao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785083/
https://ncbi.nlm.nih.gov/pubmed/17008541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-024091
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