Transmembrane and Trans-subunit Regulation of Ectodomain Shedding of Platelet Glycoprotein Ibα

Ectodomain shedding of transmembrane proteins may be regulated by their cytoplasmic domains. To date, the effecting cytoplasmic domain and the shed extracellular domain have been in the same polypeptide. In this study, shedding of GPIbα, the ligand-binding subunit of the platelet GPIb-IX complex and...

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Detalhes bibliográficos
Main Authors: Mo, Xi, Nguyen, Nam X., Mu, Fi-tjen, Yang, Wenjun, Luo, Shi-Zhong, Fan, Huizhou, Andrews, Robert K., Berndt, Michael C., Li, Renhao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952211/
https://ncbi.nlm.nih.gov/pubmed/20716526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111864
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