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Glycoprotein Ibα forms disulfide bonds with 2 glycoprotein Ibβ subunits in the resting platelet

It is widely accepted that glycoprotein (GP) Ib contains one Ibα and one Ibβ subunit that are connected by a disulfide bond. It is unclear which Cys residue in Ibα, C484 or C485, forms the disulfide bond with Ibβ. Using mutagenesis studies in transfected Chinese hamster ovary (CHO) cells, we found t...

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Podrobná bibliografie
Hlavní autoři: Luo, Shi-Zhong, Mo, Xi, Afshar-Kharghan, Vahid, Srinivasan, Sankaranarayanan, López, José A., Li, Renhao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785083/
https://ncbi.nlm.nih.gov/pubmed/17008541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-024091
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