Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114

Lignende værker

• Caught in the Act: 1.5 Å Resolution Crystal Structures of the HIV-1 Protease and the I54V Mutant Reveal a Tetrahedral Reaction Intermediate
  af: Kovalevsky, Andrey Y., et al.
  Udgivet: (2007)
• Susceptibility of Potent Antiviral Inhibitor to Highly Drug Resistant Mutations D30N, I50V and L90M of HIV-1 Protease
  af: Kovalevsky, Andrey Yu., et al.
  Udgivet: (2006)
• Effect of Flap Mutations on Structure of HIV-1 Protease and Inhibition by Saquinavir and Darunavir
  af: Liu, Fengling, et al.
  Udgivet: (2008)
• Capturing the Reaction Pathway in Near-Atomic Resolution Crystal Structures of HIV-1 Protease
  af: Shen, Chen-Hsiang, et al.
  Udgivet: (2012)
• Solution Kinetics Measurements Suggest HIV-1 Protease Has Two Binding Sites for Darunavir and Amprenavir
  af: Kovalevsky, Andrey Y., et al.
  Udgivet: (2008)