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The role of cystic fibrosis transmembrane conductance regulator phenylalanine 508 side chain in ion channel gating
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel employing the ABC transporter structural motif. Deletion of a single residue (Phe508) in the first nucleotide-binding domain (NBD1), which occurs in most patients with cystic fibrosis, impairs both maturation and function o...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1779664/ https://ncbi.nlm.nih.gov/pubmed/16484308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.099457 |
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