Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator

We have employed rate-equilibrium free energy relationship (REFER) analysis to characterize the dynamic events involved in the allosteric regulation of cystic fibrosis transmembrane conductance regulator (CFTR) function. A wide range of different hydrolysable and poorly hydrolysable nucleoside triph...

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Bibliographic Details
Main Authors: Aleksandrov, Andrei A, Cui, Liying, Riordan, John R
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2009
Subjects:
Molecular and Cellular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718247/
https://ncbi.nlm.nih.gov/pubmed/19403599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.170258
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