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Functional analysis of the C-terminal boundary of the second nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator and structural implications.

The cystic fibrosis transmembrane conductance regulator (CFTR) contains two nucleotide-binding domains (NBDs) or ATP-binding cassettes (ABCs) that characterize a large family of membrane transporters. Although the three-dimensional structures of these domains from several ABC proteins have been dete...

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Autori principali: Gentzsch, Martina, Aleksandrov, Andrei, Aleksandrov, Luba, Riordan, John R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222794/
https://ncbi.nlm.nih.gov/pubmed/12020354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020511
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