A catalytic switch and the conversion of streptokinase to a fibrin-targeted plasminogen activator

Plasminogen (Pg) activators such as streptokinase (SK) save lives by generating plasmin to dissolve blood clots. Some believe that the unique ability of SK to activate Pg in the absence of fibrin limits its therapeutic utility. We have found that SK contains an unusual NH(2)-terminal “catalytic swit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Reed, Guy L., Houng, Aiilyan K., Liu, Lin, Parhami-Seren, Behnaz, Matsueda, Lee H., Wang, Shunguang, Hedstrom, Lizbeth
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17701/
https://ncbi.nlm.nih.gov/pubmed/10430864
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados