Reprogrammed streptokinases develop fibrin-targeting and dissolve blood clots with more potency than tissue plasminogen activator

BACKGROUND: Given the worldwide epidemic of cardiovascular diseases, a more effective means of dissolving thrombi that cause heart attacks, could markedly reduce death, disability and healthcare costs. Plasminogen activators (PAs) such as streptokinase (SK) and tissue plasminogen activator (TPA) are...

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Hlavní autoři: SAZONOVA, I. Y., MCNAMEE, R. A., HOUNG, A. K., KING, S. M., HEDSTROM, L., REED, G. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911889/
https://ncbi.nlm.nih.gov/pubmed/19566545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03491.x
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