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Releasing the Brakes on the Fibrinolytic System in Pulmonary Emboli: Unique Effects of Plasminogen Activation and α2-Antiplasmin Inactivation
BACKGROUND: In patients with hemodynamically significant pulmonary embolism, physiologic fibrinolysis fails to dissolve thrombi acutely and recombinant tissue plasminogen activator (r-tPA) therapy may be required, despite its bleeding risk. To examine potential mechanisms, we analyzed the expression...
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| Udgivet i: | Circulation |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423358/ https://ncbi.nlm.nih.gov/pubmed/28028005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.024421 |
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