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Reversing the Deleterious Effects of α2-antiplasmin on Tissue Plasminogen Activator Therapy Improves Outcomes in Experimental Ischemic Stroke

High blood levels of α2-antiplasmin have been associated with failed tissue plasminogen activator (TPA) therapy for ischemic stroke. Yet, other data suggests that α2-antiplasmin may be protective in stroke, because it defends against bleeding and excitotoxicity. To address this paradox, we examined...

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Hlavní autoři: Houng, Aiilyan K., Wang, Dong, Reed, Guy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066326/
https://ncbi.nlm.nih.gov/pubmed/24556477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.02.009
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