Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm

Mutational inactivation of the adenomatous polyposis coli (APC) tumor suppressor initiates most hereditary and sporadic colon carcinomas. Although APC protein is located in both the cytoplasm and the nucleus, the protein domains required to maintain a predominantly cytoplasmic localization are unkno...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Neufeld, Kristi L., Nix, David A., Bogerd, Hal, Kang, Yibin, Beckerle, Mary C., Cullen, Bryan R., White, Raymond L.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2000
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220401797
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