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Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein

Mutation of the adenomatous polyposis coli (APC) gene is an early step in the development of colorectal carcinomas. APC protein is located in both the cytoplasm and the nucleus. The objective of this study was to define the nuclear localization signals (NLSs) in APC protein. APC contains two potenti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zhang, Fang, White, Raymond L., Neufeld, Kristi L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230435597
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