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Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein

Mutation of the adenomatous polyposis coli (APC) gene is an early step in the development of colorectal carcinomas. APC protein is located in both the cytoplasm and the nucleus. The objective of this study was to define the nuclear localization signals (NLSs) in APC protein. APC contains two potenti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Zhang, Fang, White, Raymond L., Neufeld, Kristi L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230435597
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