Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein

Mutation of the adenomatous polyposis coli (APC) gene is an early step in the development of colorectal carcinomas. APC protein is located in both the cytoplasm and the nucleus. The objective of this study was to define the nuclear localization signals (NLSs) in APC protein. APC contains two potenti...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Zhang, Fang, White, Raymond L., Neufeld, Kristi L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2000
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230435597
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