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Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein

Mutation of the adenomatous polyposis coli (APC) gene is an early step in the development of colorectal carcinomas. APC protein is located in both the cytoplasm and the nucleus. The objective of this study was to define the nuclear localization signals (NLSs) in APC protein. APC contains two potenti...

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Détails bibliographiques
Auteurs principaux: Zhang, Fang, White, Raymond L., Neufeld, Kristi L.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC18806/
https://ncbi.nlm.nih.gov/pubmed/11050185
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