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Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm

Mutational inactivation of the adenomatous polyposis coli (APC) tumor suppressor initiates most hereditary and sporadic colon carcinomas. Although APC protein is located in both the cytoplasm and the nucleus, the protein domains required to maintain a predominantly cytoplasmic localization are unkno...

詳細記述

保存先:
書誌詳細
主要な著者: Neufeld, Kristi L., Nix, David A., Bogerd, Hal, Kang, Yibin, Beckerle, Mary C., Cullen, Bryan R., White, Raymond L.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC17298/
https://ncbi.nlm.nih.gov/pubmed/11035805
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