Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm

Mutational inactivation of the adenomatous polyposis coli (APC) tumor suppressor initiates most hereditary and sporadic colon carcinomas. Although APC protein is located in both the cytoplasm and the nucleus, the protein domains required to maintain a predominantly cytoplasmic localization are unkno...

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書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Neufeld, Kristi L., Nix, David A., Bogerd, Hal, Kang, Yibin, Beckerle, Mary C., Cullen, Bryan R., White, Raymond L.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2000
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220401797
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