ロード中...
Mechanisms of genotoxin-induced transcription and hypermutation in p53
It is widely assumed that genotoxin-induced damage (e.g., G-to-T transversions) to the tumor suppressor gene, p53, is a direct cause of cancer. However, genotoxins also induce the stress response, which upregulates p53 transcription and the formation of secondary structures from ssDNA. Since unpaire...
保存先:
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2006
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1702552/ https://ncbi.nlm.nih.gov/pubmed/17140443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-6-27 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|