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Mechanisms of transcriptional regulation by p53

p53 is a transcription factor that suppresses tumor growth through regulation of dozens of target genes with diverse biological functions. The activity of this master transcription factor is inactivated in nearly all tumors, either by mutations in the TP53 locus or by oncogenic events that decrease...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Sullivan, Kelly D, Galbraith, Matthew D, Andrysik, Zdenek, Espinosa, Joaquin M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729533/
https://ncbi.nlm.nih.gov/pubmed/29125602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.174
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