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Mechanisms of transcriptional regulation by p53
p53 is a transcription factor that suppresses tumor growth through regulation of dozens of target genes with diverse biological functions. The activity of this master transcription factor is inactivated in nearly all tumors, either by mutations in the TP53 locus or by oncogenic events that decrease...
Enregistré dans:
| Publié dans: | Cell Death Differ |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5729533/ https://ncbi.nlm.nih.gov/pubmed/29125602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.174 |
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