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Characterization of bacteriophage T4-coordinated leading- and lagging-strand synthesis on a minicircle substrate

The DNA replication complex of bacteriophage T4 has been assembled as a single unit on a minicircle substrate with a replication fork that permits an independent measurement of the amount of DNA synthesis on both the leading and lagging strands. The assembled replisome consists of the T4 polymerase...

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Autores principales: Salinas, Frank, Benkovic, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC16522/
https://ncbi.nlm.nih.gov/pubmed/10860983
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