Coordinated Leading and Lagging Strand DNA Synthesis by Using the Herpes Simplex Virus 1 Replication Complex and Minicircle DNA Templates

The origin-specific replication of the herpes simplex virus 1 genome requires seven proteins: the helicase-primase (UL5-UL8-UL52), the DNA polymerase (UL30-UL42), the single-strand DNA binding protein (ICP8), and the origin-binding protein (UL9). We reconstituted these proteins, excluding UL9, on sy...

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Hlavní autoři: Stengel, Gudrun, Kuchta, Robert D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020029/
https://ncbi.nlm.nih.gov/pubmed/21068232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01688-10
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