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Processing of Lagging-Strand Intermediates In Vitro by Herpes Simplex Virus Type 1 DNA Polymerase

The processing of lagging-strand intermediates has not been demonstrated in vitro for herpes simplex virus type 1 (HSV-1). Human flap endonuclease-1 (Fen-1) was examined for its ability to produce ligatable products with model lagging-strand intermediates in the presence of the wild-type or exonucle...

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Detalhes bibliográficos
Main Authors: Zhu, Yali, Wu, Zetang, Cardoso, M. Cristina, Parris, Deborah S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897638/
https://ncbi.nlm.nih.gov/pubmed/20444887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01875-09
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