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Herpes Simplex Virus Type 1 Helicase-Primase: DNA Binding and Consequent Protein Oligomerization and Primase Activation

The heterotrimeric helicase-primase complex of herpes simplex virus type I (HSV-1), consisting of UL5, UL8, and UL52, possesses 5′ to 3′ helicase, single-stranded DNA (ssDNA)-dependent ATPase, primase, and DNA binding activities. In this study we confirm that the UL5-UL8-UL52 complex has higher affi...

詳細記述

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書誌詳細
主要な著者: Chen, Yan, Bai, Ping, Mackay, Shannon, Korza, George, Carson, John H., Kuchta, Robert D., Weller, Sandra K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019990/
https://ncbi.nlm.nih.gov/pubmed/21068246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01690-10
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