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Initiation of New DNA Strands by the Herpes Simplex Virus-1 Primase-Helicase Complex and Either Herpes DNA Polymerase or Human DNA Polymerase α

A key set of reactions for the initiation of new DNA strands during herpes simplex virus-1 replication consists of the primase-catalyzed synthesis of short RNA primers followed by polymerase-catalyzed DNA synthesis (i.e. primase-coupled polymerase activity). Herpes primase (UL5-UL52-UL8) synthesizes...

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Detalhes bibliográficos
Main Authors: Cavanaugh, Nisha A., Kuchta, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615532/
https://ncbi.nlm.nih.gov/pubmed/19028696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805476200
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