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Protein Displacement by Herpes Helicase-Primase and the Key Role of UL42 During Helicase-Coupled DNA Synthesis by the Herpes Polymerase
The herpes helicase-primase (UL5-UL8-UL52) very inefficiently unwinds double stranded DNA. To better understand the mechanistic consequences of this inefficiency, we investigated protein displacement activity by UL5-UL8-UL52, as well as the impact of coupling DNA synthesis by the herpes polymerase w...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648053/ https://ncbi.nlm.nih.gov/pubmed/28505413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01128 |
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