SOS mutator activity: Unequal mutagenesis on leading and lagging strands

A major pathway of mutagenesis in Escherichia coli is mediated by the inducible SOS response. Current models of SOS mutagenesis invoke the interaction of RecA and UmuD′(2)C proteins with a stalled DNA replication complex at sites of DNA lesions or poorly extendable terminal mismatches, resulting in...

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Huvudupphovsmän: Maliszewska-Tkaczyk, Magdalena, Jonczyk, Piotr, Bialoskorska, Malgorzata, Schaaper, Roel M., Fijalkowska, Iwona J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC18823/
https://ncbi.nlm.nih.gov/pubmed/11050167
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