Enzymatic completion of mammalian lagging-strand DNA replication.

Using purified proteins from calf and a synthetic substrate, we have reconstituted the enzymatic reactions required for mammalian Okazaki fragment processing in vitro. The required reactions are removal of initiator RNA, synthesis from an upstream fragment to generate a nick, and then ligation. With...

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Dades bibliogràfiques
Autors principals: Turchi, J J, Huang, L, Murante, R S, Kim, Y, Bambara, R A
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC44905/
https://ncbi.nlm.nih.gov/pubmed/7524089
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