SOS mutator activity: Unequal mutagenesis on leading and lagging strands
A major pathway of mutagenesis in Escherichia coli is mediated by the inducible SOS response. Current models of SOS mutagenesis invoke the interaction of RecA and UmuD′(2)C proteins with a stalled DNA replication complex at sites of DNA lesions or poorly extendable terminal mismatches, resulting in...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18823/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220424697 |
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