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Characterization of bacteriophage T4-coordinated leading- and lagging-strand synthesis on a minicircle substrate

The DNA replication complex of bacteriophage T4 has been assembled as a single unit on a minicircle substrate with a replication fork that permits an independent measurement of the amount of DNA synthesis on both the leading and lagging strands. The assembled replisome consists of the T4 polymerase...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Salinas, Frank, Benkovic, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16522/
https://ncbi.nlm.nih.gov/pubmed/10860983
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