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Simultaneous formation of functional leading and lagging strand holoenzyme complexes on a small, defined DNA substrate

The biochemical characterization of leading and lagging strand DNA synthesis by bacteriophage T4 replication proteins has been addressed utilizing a small, defined primer/template. The ATP hydrolysis activity of 44/62, the clamp loading complex responsible for holoenzyme assembly, was monitored duri...

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Detalhes bibliográficos
Main Authors: Berdis, Anthony J., Benkovic, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21607/
https://ncbi.nlm.nih.gov/pubmed/9736701
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