Llwytho...

Structural and dynamical changes in an α-subunit of a heterotrimeric G protein along the activation pathway

The Gα subunits of heterotrimeric G proteins (Gαβγ) mediate signal transduction via activation by receptors and subsequent interaction with downstream effectors. Crystal structures indicate that conformational changes in “switch” sequences of Gα, controlled by the identity of the bound nucleotide (G...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Van Eps, Ned, Oldham, William M., Hamm, Heidi E., Hubbell, Wayne L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637559/
https://ncbi.nlm.nih.gov/pubmed/17053066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607972103
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