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Tracing the evolution of the heterotrimeric G protein α subunit in Metazoa

BACKGROUND: Heterotrimeric G proteins are fundamental signaling proteins composed of three subunits, Gα and a Gβγ dimer. The role of Gα as a molecular switch is critical for transmitting and amplifying intracellular signaling cascades initiated by an activated G protein Coupled Receptor (GPCR). Desp...

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Detalles Bibliográficos
Publicado en:BMC Evol Biol
Autores principales: Lokits, A. D., Indrischek, H., Meiler, J., Hamm, H. E., Stadler, P. F.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896119/
https://ncbi.nlm.nih.gov/pubmed/29642851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-018-1147-8
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